Moreover, the difference analysis between high and low expression level of IL2RA in ccRCC illustrated that the high IL2RA expression set presented a significantly larger fraction of native B cells, CD4+ memory T cells, and M2 macrophages, than CD8+ T cells, NK cells, and neutrophils (p < 0.05, Figure 5D). Here, CD4 is linked to nonpapillary renal cell carcinoma.