Fusion or mutation of IGLL5 was identified in Burkitt lymphoma, multiple lymphadenopathy, diffuse large B cell lymphoma, multiple myeloma, and chronic lymphocytic leukemia (Kasar et al., 2015; White et al., 2018; Panea et al., 2019; Li et al., 2020; Mosquera Orgueira et al., 2021). Here, IGLL5 is linked to plasma cell myeloma.