Activity of the AR pathway, and to a lesser extent of the TGFβ signaling pathway, was increased in sepsis, while a trend toward higher activity was observed for MAPK-AP1, ER, NFκB and JAK-STAT3 pathways, toward lower activity for the Hedgehog pathway, while activity of the JAK-STAT1/2 pathway did not differ between healthy controls and sepsis patients. Here, NFKB1 is linked to Sepsis.