PAS scores for the AR, ER, MAPK-AP1, FOXO-PI3K, JAK-STAT1/2, JAK-STAT3, Notch, Hedgehog, TGFβ, and NFκB pathways were measured using target gene expression data of whole blood samples from clinical studies on children (Supplementary Figures 1–6) and adults with sepsis and septic shock (Supplementary Figures 7, 8). The gene discussed is STAT1; the disease is Sepsis.