GATA3 and infection: In the V. cholerae zebrafish model, mRNA gene expression of both T-bet and GATA3 was significant increased at all three time points after V. cholerae infection, suggesting that both pandemic and non-pandemic V. cholerae strains (El Tor and non-O1) can induce Th1 and Th2 cell mediated adaptive immune responses following infection (Figure 1).