CCND1 and mantle cell lymphoma: The translocation t (11,14)(q13;q32) is considered the primary oncogenic event in over 95% of MCL cases that results in the juxtaposition of immunoglobulin heavy-chain (IGH) enhancer region on 14q32 next to CCND1 on 11q13, resulting in its overexpression (1, 5, 6).