On the other hand, in the mTOR signaling pathway, the WD repeat domain 24; disheveled segment polarity protein 1; HRas proto-oncogene, GTPase; Unc-51 like autophagy activating kinase 1; serine/threonine kinase 11 (STK11); and telomere maintenance 2 genes were downregulated in the OSA-HTN group, but not in the non-OSA group (Table 4). This evidence concerns the gene ULK1 and obstructive sleep apnea syndrome.