Multiple Cox regression models included serum GGT as a continuous variable as well as traditional risk factors (age, sex, smoking status, diabetes, LDL cholesterol, systolic blood pressure (SBP), and past cardiovascular (CV) events), hepatic disease-related factors (transaminases (AST/ALT), alkaline phosphatase (Alk_P), and alcohol consumption), body mass index (BMI), hemoglobin, oxidized LDL, C-reactive protein (CRP), homocysteine, and creatinine clearance. The gene discussed is CRP; the disease is diabetes mellitus.