Similarly, Sato et al. demonstrated in a T-anaplastic large cell lymphoma cell line (T-ALCL), Karpas 299, that CD26 modulates the phosphorylation of β1 integrin by inducing the activation of p38 Mitogen Activated Protein Kinase (MAPK) (47). This evidence concerns the gene DPP4 and anaplastic large cell lymphoma.