MYC and cancer: Accumulated evidence suggests that c-MYC-driven metabolic reprogramming in cancer cells is mainly characterized by increased uptake of precursors, enhanced rate of glycolysis and glutaminolysis, as well as increased synthesis of fatty acids and nucleotides (Cunningham et al., 2014; Broecker-Preuss et al., 2017; Cai et al., 2019; Casciano et al., 2020).