IL6 and systemic lupus erythematosus: Alternatively, increased numbers of Selenomonas, Veillonella, T. denticola, and Leptotrichia are directly associated with raised concentrations of inflammatory factors like IL-6, IL-17, and IL-33, which are indicative of a decline in oral microbial species diversity in SLE patients (Corrêa et al., 2017).