IGF-1 supplementation in rodent models of middle cerebral artery occlusion and photothrombotic stroke reduces the size of infarcted tissue and the accompanying sensorimotor deficits, even when administered in the days after insult (Liu et al., 2001; Bake et al., 2014, 2016; Parker et al., 2017; Serhan et al., 2019; Hayes et al., 2021). Here, IGF1 is linked to Stroke.