TCR sequencing of PD-L1-specific SKILs (a more specific culture than IDO/PD-L1-specific isolations derived from PBMCs on vaccination) and paired biopsies showed that two of the top five PD-L1-specific SKIL clones were present at the tumor site both before and after treatment (Extended Data Fig. 7e,f). The gene discussed is CD274; the disease is neoplasm.