The survival curves for patients with different serum CRP levels (shown in Fig. 1c) show similar patterns as those observed in patients with different tumour grading (shown in Fig. 1a)50,51, which is the main variable for the WHO-classification of neuroendocrine disease39,40 and implemented in the European Neuroendocrine Tumour Society (ENETS) guidelines5. The gene discussed is CRP; the disease is neoplasm.