Note that the protective role of NF-YB in STAD is opposite to what we reported in HCC iCluster1 tumors, generally associated to wt p53 status: although direct NF-Y/p53 interactions have been reported in several studies20, the reasons for association of NF-YB levels to such genetic background is unclear. The gene discussed is NFYB; the disease is hepatocellular carcinoma.