To confirm that participants with the lowest IFN induction had adverse clinical outcomes in relation to the most common respiratory viral infections (RVs and RSV), we compared frequencies of hospitalizations for LRTIs and bronchiolitis (the great majority of which are caused by RVs and RSV) in participants with IFN-α induction in response to RV-A16 and RSV below the 15th percentile, with frequencies in participants with responses above the 15th percentile. This evidence concerns the gene IFNA1 and bronchiolitis.