With the strong effect on recruitment and activation of DCs, QD-Cat-RGD-based RT consequently caused an increase in tumor-infiltrated T cells (CD3+) and cytotoxic CD8+ T cells (CD8+CD3+) compared with RT alone (Fig. 5c, d and Supplementary Fig. 11d), which led to a strong T cell-mediated antitumor immune response43. This evidence concerns the gene CD8A and neoplasm.