CD8A and neoplasm: Treatment combining QD-Cat-RGD-based RT with aCD8 caused decreases in tumor-infiltrated T cells (CD3+) and depletion of cytotoxic CD8+ T cells (CD8+CD3+) (Supplementary Fig. 12e,f), confirming that the antitumor effect in primary tumor was mainly induced by CD8+ cytotoxic T cells in the TME.