VWF and vasculitis: These strong correlations between the concentration of platelet aggregates and the WBC, FVIII, VWF:RCo, and TM levels indicate that the high concentration of platelet aggregates is linked with systemic microthrombus formation and fibrinolysis, which are expressed by the high D-dimer level, and with vascular endothelial damage (i.e., vasculitis), which is expressed by the high FVIII, VWF:RCo, and TM levels.