As revealed by comparison with colonic mucosa from non-cancer individuals, both transformed and non-transformed tissue from CRC patients had upregulated CCL2 (5.3- and 11.1-fold, respectively), CCL7 (1.9- and 2.3-fold), and CCL8 (2.1- and 8.3-fold), although non-significantly in the case of tumor CCL8. The gene discussed is CCL8; the disease is cancer.