The adeno-associated virus 1-based vector (AAV-miR-7) was used for delivery, and the resulting expression of miR-7 in the striatum reduced the levels of both monomeric, including phosphorylated, and aggregated alpha-synuclein, attenuated neurodegeneration, neuroinflammation, and behavioral deficits that are typical for this mouse model of alpha-synucleinopathy [49]. The gene discussed is SNCA; the disease is synucleinopathy.