Thus, we subjected the cells to 4 °C for 5 min, under MG-132 treatment, and then we performed an immunofluorescence staining using a human anti-CREST (Raynaud’s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasias) antibody to localize the kinetochores, and an anti-α-tubulin antibody to visualize the spindle microtubules. This evidence concerns the gene SS18L1 and Telangiectasia.