NFKB1 and familial pancreatic carcinoma: Microsclerodermin A, 73 and B, 74 inhibit NF-κB transcriptional activity leading to reduction of levels of phosphorylated (active) NF-κB in the AsPC-1 cell line, against the AsPC-1, BxPC-3, MIA PaCa-2 and PANC-1 pancreatic cancer cell lines, and induce significant apoptosis in the AsPC-1, BxPC-3 and the PANC-1 cell lines [94].