NFKB1 and Familial prostate cancer: In vitro studies on Glycyrrhizic acid (Glycyrrhizin), 123, a triterpenoid glycoside from the roots of the plant, showed that the compound downregulates pro-inflammatory modulators NF-κB and thromboxane synthase causing apoptosis on lung adenocarcinoma, hepatoma, leukemia, stomach, and prostate cancer cell lines (Figure 19) [160,161,162].