Furthermore, the data reported here show that LPE is able to inhibit the rIL-6-dependent cell migration and invasiveness in human primary T88 and T93 colon cancer cells [30,31,32] via the up-regulation of MMP-2 expression, and that the observed effects correlate with the STAT3 phosphorylation levels. The gene discussed is STAT3; the disease is colonic neoplasm.