PCAT6 and posterior cortical atrophy: Lang et al. discovered that PCAT6 upregulating by methyltransferase 3 (METTL3), a catalytic subunit of the N6-adenosine-methyltransferase complex that induces m6A modification, promoted PCa cell proliferation and metastasis in vitro, and accelerated tumor growth and bone metastasis (BM) in vivo.