However, such an approach could also be considered for other molecularly-defined tumor entities including Group 4 (often subtype IV) medulloblastomas with chromosome 11 loss, completely resected ST-YAP1 ependymomas, completely resected PF-B ependymomas without 13q loss, and ‘infant’ or ‘LGG-like’ pediatric HGGs. The gene discussed is YAP1; the disease is neoplasm.