CHFR and ovarian carcinoma: Because the vast majority of patients receiving paclitaxel (alone or in combination with bevacizumab) for relapsed ovarian cancer do not have pretreatment biopsies immediately prior to initiation of paclitaxel therapy, we turned to a unique set of PDXs treated with paclitaxel monotherapy (Table 1) to further assess the relationship between CHFR expression and response.