SLC7A5 and cancer: In particular, the vast majority of neoplastic tissues, such as gliomas, breast, and prostate cancers, prominently overexpress the system L amino acid transporter LAT1 [3,8,9,10] and other amino acid transporters, such as ASCT2 [11,12], which have been identified as “cancer-promoting targets” and part of the “tumor metabolome” [11,13].