To investigate the role of the Kv11.1 channel in colon cancer cell motility, we selected a panel of cells expressing the Kv11.1 channel (Figure 1A–C) and performed a wound-healing assay before and after treatment with Kv11.1 activator molecule NS1643 for 16 h (Figure 1D,E). Here, KCNH2 is linked to malignant colon neoplasm.