MYOM2 and plasma cell myeloma: The International Myeloma Working Group (IMWG) set the thresholds of 1 g/dL serum M-protein and 200 mg/24 h urine M-protein to define a measurable disease, while lower levels of M-protein identify unmeasurable disease, which is further classified as oligo-secretory (OS), non-secretory (NS) or non-producer MM [3].