More recently, Josefsson et al. also reported a high 50% HER2 detection rate with a similar method to ours (PCR pre-amplification followed by qPCR) in CTCs of a cohort of 22 patients with PCa bone metastases (7 mHSPC and 15 mCRPC) [17]. Here, ERBB2 is linked to posterior cortical atrophy.