TAAs comprise of differentiation antigens (e.g., melanocyte differentiation antigens), overexpressed cellular antigens (e.g., HER2, MUC-1, CEA), wild-type p53 protein or cancer/testis antigens expressed in germ cells but also activated in cancer cells (e.g., MAGE, NY ESO-1) [32,33]. This evidence concerns the gene CEACAM5 and cancer.