LRRK2 and Parkinson disease: Other genes implicated in genetic forms of Parkinsonism, like PINK1 (PTEN-induced kinase 1), LRRK2 (Leucine-rich repeat kinase 2), PARK7 (Parkinsonism associated deglycase, also known as DJ-1) have also been shown to be relevant in the development of neoplasms, where they interfere in the regulation of processes such as cell cycle, apoptosis, mitochondrial homeostasis and oxidative stress.