For this, we curated a gene list based on a literature search on commonly disrupted pathways in both cancer and neurodegeneration with a focus in PD, which included several KEGG pathways, namely immune system (Table S2), DNA damage (Table S3), cell cycle (Table S4), redox homeostasis (from energy metabolism and catabolism pathways) (Table S5), a published list of core-clock genes comprising the core-clock network (CCN) and the ECCN [87,88], (Table S6), and the PD pathway (Table S7). The gene discussed is CLOCK; the disease is cancer.