Furthermore, a subsequent analysis on the possible role of the altered genes in CRC and IPD data sets in the survival of cancer patients (TCGA-COAD data sets) pointed to a significant influence on survival for eight of these genes (TUBB6, PAK6, SULT1A1, SLC11A1, TRAP1, FAM50B, SPON2, FES). Here, SPON2 is linked to cancer.