NK cells and ILC1 express the transcription factors Eomesodermin (EOMES) and T-box transcription factor 21 (T-BET), which drive the production of interferon (IFN)-γ and cytotoxic molecules such as granzymes and perforin, key features involved in the elimination of virus-infected and tumor cells [9,10,11]. This evidence concerns the gene EOMES and neoplasm.