SSTR2 and neoplasm: In practice, this turned out to be more complicated than expected, because compared to SSTR2-expression in NET, αvβ3-integrin expression showed a higher degree of interindividual variation for most tumor entities, and αvβ3-integrin dependent uptake in target-positive lesions is usually substantially lower as compared to SSTR2-mediated accumulation of radiopharmaceuticals [43,44].