Similar studies were conducted using Ishikawa cells, a cell line derived from an endometrial adenocarcinoma, and revealed that transfected miR-98, a Let-7 family member [65], suppressed PGRMC1 expression through a direct interaction with the 3′-UTR region of PGRMC1 [60]. Here, PGRMC1 is linked to endometrium adenocarcinoma.