Quantitative PCR measurements confirm that PGRMC1 expression increases as ovarian tumors progress from stage 1 in which the cancer cells are restricted to the ovary and fallopian tubes through stage 4 when the ovarian cancer cells have metastasized to various sites throughout the body (https://www.cancer.org/cancer/ovarian-cancer/detection-diagnosis-staging/staging.html, accessed on 15 September 2021). Here, PGRMC1 is linked to ovarian cancer.