From our analysis, several members of this polycistron were hypomethylated, including MIR17HG, a known promoter of tumorigenesis and metastasis in CRC [60], miR-18a (miR-18a) having been shown to be important in prostate cancer [61], breast cancers [62], osteosarcoma [63], and nasopharyngeal carcinoma [64]. Here, MIR17HG is linked to osteosarcoma.