The aberrational regulation of miRs has been shown to interfere with several important signaling cascades including epidermal growth factor receptor (EGFR), kirsten rat sarcoma virus (KRAS), PI3K, Wingless and Int-1 (Wnt), myelocytomatosis (Myc), HIPO and Notch pathways, amongst others, which are vital to tumor progression and metastasis [12]. The gene discussed is EGFR; the disease is neoplasm.