The matrix metalloproteases 1 (MMP1), MMP2, and MMP14 have been functionally associated with the shedding of sCD26/DPP4 from smooth muscle cells, while MMP9 has been implicated in the release of the soluble form from adipocytes [13] and MMP10/13 from ovarian cancer cells [14]. Here, MMP1 is linked to ovarian carcinoma.