BANCR and metastatic malignant neoplasm in the lymph nodes: Likewise, Yao et al. observed markedly upregulated BANCR expression in OSCC tissues; more importantly, a multivariate proportional hazards (COX) regression analysis revealed that in addition to lymph node metastasis, BANCR expression level was independently associated with poor overall survival (OS) and disease-free survival (DFS), which suggests BANCR was an independent prognostic factor in OSCC patients [23].