ORAI3 and pachyonychia congenita: As expected, we observed noticeably higher bio-fluorescence intensity (marked in red circles) in the case of shNT Panc1 stables injected mice (Figure 9B) in comparison to the shOrai3 Panc1 stables injected group (Figure 9B’) suggesting that Orai3 plays a critical role in PC metastasis.