The topmost molecular network in the intestinal subtype on IPA network analysis showed increased expression of SULF1 [62], HGF [63,64], SPARC [65,66,67], SERPINH1 [68], and IGFBP7 [69,70], which have been shown to contribute to the growth and survival of tumor cells, tumor invasion, metastasis, and poor survival in gastric cancer (Supplementary Figure S2). This evidence concerns the gene SPARC and gastric cancer.