In a study by Wu et al., where they studied the correlation between mRNA expression of B-cell lymphoma 2 interacting mediator of cell death (BIM), astrocyte elevated gene-1 (AEG-1) and AXL receptor tyrosine kinase (AXL) and OS in gastric cancer, no association between mRNA expression and OS for any of these genes following first-line chemotherapy with folinic acid, 5-fluorouracil (5-FU), and oxaliplatin (FOLFOX) was found [121]. This evidence concerns the gene MTDH and gastric cancer.