APC and urinary bladder cancer: Besides, our analysis highlighted several attributed genes and their associated signaling network involved in bladder cancer prognosis, including the family of ubiquitin-conjugating enzymes (UBE2C, UBE2D1, and UBE2E1), regulatory protein involved in mitosis (CCNB1), cell division cycle protein ubiquitin ligase (CDC16, CDC23, and CDC26) that are components of the multiprotein APC complex.