CXCR4 and hematologic disorder: However, in hematologic diseases, profound myeloablation by CXCR4-targeted RLT prior to autologous or allogeneic hematopoietic transplantation is a desired effect that has already been enhanced by the addition of anti-cluster of differentiation 66 (CD66)-directed or anti-CD20-directed radioimmunotherapy in some cases [39].