Since other studies did not find any evidence for associations between the genetic variations of different TASR2s and the susceptibility to these types of cancer [39,42,43,46,49] or even identified a decreased risk for the non-tasting TAS2R38 diplotype [45], the question of whether specific TAS2Rs and/or their variants, resulting in a distinct bitter sensitivity, play a functional role in carcinogenesis in a population group characterized by dietary habits and/or socio-demographic factors such as age or sex has still to be elucidated. Here, TAS2R38 is linked to cancer.