A study on the functionality of TAS2Rs in neuroblastoma [22] showed an inhibition of the self-renewal capacity as well as migration and invasion, due to over-expression of TAS2R8 or TAS2R10 in transfected SK-N-BE(2)C, which is a less differentiated neuroblastoma cell line. The gene discussed is TAS2R10; the disease is neuroblastoma.