U2AF1 and CD4+/CD56+ hematodermic neoplasm: Summerer et al. [28] analyzed 1367 mutations in 1210 genes in 21 BPDCN cases and found mutations in SRSF2 in 7 (33%), SF3B1 in 2 (10%), U2AF1 in 2 (10%), and ZRSR2 in 2 (10%) cases.