CD8A and neoplasm: A deficiency of basic leucine zipper ATF-like transcription factor 3 (BATF3), a transcription factor required for cDC differentiation and programming CD8+ T cell memory [37,38], resulted in a defective DC-associated, cytotoxic T cell-mediated anti-tumor immunity [39] and natural killer (NK) cell-suppressed metastasis in vivo [40].