As reported in breast and ovarian cancers [19,20,26], we confirmed that primary CAF-S1 cells co-cultured with CD4+ CD25+ T cells significantly increased the percentage of CD4+ CD25+ FOXP3+ T lymphocytes (Fold-change = 1.6) (Figure 3A,B), with a strong impact on CD4+ CD25+ FOXP3high sub-population (Fold-change = 4.2) (Figure 3B, right). The gene discussed is CD4; the disease is ovarian cancer.