MiR-214 was found to downregulate CXCR4, SESN3, and PD-L1, while knockdown of miR-214 markedly increased CXCR4, SESN3, and PD-L1 above basal levels in PC3 and MDA-PCa-2b cells. This evidence concerns the gene CXCR4 and posterior cortical atrophy.