ACTA2, IGFBP7, TAGLN, MYL9, and MYLK are significantly overexpressed in cluster 23 compared with other PDGFRα/β+ cells, suggesting that this subpopulation may indeed be a ccRCC CAF population (Figure 3C, Table S6) [46,47,48]. This evidence concerns the gene MYLK and nonpapillary renal cell carcinoma.