MME and neoplasm: First, we categorized clustered data into tumor and stromal populations using a panel of markers for each (epithelial: AQP1, AQP2, EPCAM; endothelial: PLVAP, CD31, CD34; fibroblast: PDGFRα, PDGFRβ; immune: CD45; tumor cell: CXCR4, VIM, KRT18, PAX8, PAX2, CA9, CD10) (Figure 3A, Table S4).