The elevated prevalence in Hashimoto’s thyroiditis may either result from SELENOP-aAb predisposing them to the diseases—as low Se has been identified as risk factor for autoimmune thyroid disease [31,32,33]—or the autoimmunity develops as a consequence of the ongoing inflammation and associated oxidative damage to thyroid proteins, i.e., resulting from the lymphocytic thyroiditis and generation of novel autoantigens as side effect of disease [8,34]. The gene discussed is SELENOP; the disease is Hashimoto thyroiditis.