PDGFA and glioblastoma: Similarly, loss of microglial Olfml3 abolished the TGFβ-induced increase in Pdgfa mRNA, a key negative prognostic indicator in GBM [37] (β1: 2.3 ± 0.6 vs. 1.6 ± 0.6, p < 0.05); β2: 2.7 ± 0.5 vs. 1.4 ± 0.1; β3: 3.3 ± 0.6 vs. 1.2 ± 0.2, p < 0.01) (Figure 5J).