Several chemokines and receptors, including CXCL9, 10, 11, 12, 13, and CXCR3 and CXCR4, were found in high concentrations in the serum of patients with SJIA or AOSD, and these correlated with several disease activity markers of SJIA or AOSD [96,97,126,127]. The gene discussed is CXCR4; the disease is adult-onset Still disease.