Such a negative regulator, like OsNPR1 [38], 9-lipoxygenase (Osr9-LOX1) [39], OsWRKY53 [40], and MPK20-5 [41] reported previously in rice, may help ensure appropriate levels of JA, JA-Ile, and ABA in rice plants when infested by BPH, thereby avoiding the autotoxicity that excessive plant defenses may lead to. The gene discussed is OLR1; the disease is benign prostatic hyperplasia.